反应详情

温度

80 °C

A mixture of 1d (3.5 g, 13.5 mmol), dimethoxyethane (100 ml) and aqueous sodium hydroxide (50 ml, 1 M) is heated to 80° C. for 1 hour. After cooling the mixture is poured into ice-water. The product is filtered off, washed with water and dried. Yield 2.77 g (94%). Mp 109-1 10° C.

1. temperatureAfter cooling the mixture
2. filtrationThe product is filtered off
3. washwashed with water
4. customdried
5. customMp 109-1 10° C.