反应详情

5-acetyl-2-(3-(3-pyridyl)phenylamino)aniline (5 g, 16.5 mmol) in formic acid (50 ml) is stirred at 90° C. for 1.5 hours. The cooled reaction mixture is made alkaline by addition of 12 M NaOH. 5-acetyl-1-(3-(3-pyridyl)phenyl)benzimidazole is filtered off washed with water and dried. Quantitative yield. m.p. 195-97° C.

1. customThe cooled reaction mixture
2. filtration5-acetyl-1-(3-(3-pyridyl)phenyl)benzimidazole is filtered off
3. washwashed with water
4. customdried