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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 582020Generated: October 25, 2026

Potassium Carbonate → 2,4,6-Tris(1-methyl-3-trifluoromethylpyrazol-5-yloxy)pyridine

https://huagongshe.com/reaction/582020

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2,4,6-TrifluoropyridineHCID 2783289—
ReactantHCID 178481859HCID 178481859—
SolventSulfolaneHCID 31347—
Product2,4,6-Tris(1-methyl-3-trifluoromethylpyrazol-5-yloxy)pyridineHCID 15869678—

Reaction Conditions

Temperature80 °C

Reaction Steps

A stirred mixture of 2,4,6-trifluoropyridine (4.8 g, 36 mmol), 5-hydroxy-1-methyl-3-trifluoromethylpyrazole (19.8 g, 119 mmol) and potassium carbonate (18.1 g, 131 mmol) in anhydrous sulfolane (25 ml) is heated to 80° C. over a period of 3 days.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05922738
Source datasetuspto-grants-1999_07
ORD IDord-2e3c5cffd801481fb6c6cb10484d4176
Source noteuspto-grants-1999_07