HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Oxalyl chloride → 2-Methoxy-5-(trifluoromethoxy)benzoyl chloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Oxalyl chloride | HCID 65578 | — |
| Edukt | 2-methoxy-5-(trifluoromethoxy)benzoic Acid | HCID 2775286 | — |
| Katalysator | Dimethylformamide | HCID 6228 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 2-Methoxy-5-(trifluoromethoxy)benzoyl chloride | HCID 3580596 | — |
Reaktionsschritte
Combine 2-methoxy-5-trifluoromethoxybenzoic acid (0.6 g, 2.53 mmol) and dichloromethane (10 mL). Cool in an ice bath. Add dropwise oxalyl chloride (0.64 mL, 5.0 mmol) followed by dimethylformamide (1 drop). Warm to ambient temperature. After 3 hours, evaporate invCacuo and dry to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05922737 |
| Quelldatensatz | uspto-grants-1999_07 |
| ORD ID | ord-7609941b8e234f45a798d8f04e31586a |
| Quellennotiz | uspto-grants-1999_07 |