Butyryl chloride → N-[2-(5-Methoxy-1H-inden-3-yl)ethyl]butyramide

HRID 582217Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:11]=[C:10]2[C:6]([CH2:7][CH2:8][C:9]2=[CH:12][CH2:13][NH2:14])=[CH:5][CH:4]=1.[C:15](Cl)(=[O:19])[CH2:16][CH2:17][CH3:18]>>[CH3:1][O:2][C:3]1[CH:11]=[C:10]2[C:6](=[CH:5][CH:4]=1)[CH2:7][CH:8]=[C:9]2[CH2:12][CH2:13][NH:14][C:15](=[O:19])[CH2:16][CH2:17][CH3:18]

Participants

Reactant 2

HCID 8855Butyryl chloride

HCID 545094892-(6-Methoxyindan-1-ylidene)ethylamine

Product 1

HCID 54521852N-[2-(5-Methoxy-1H-inden-3-yl)ethyl]butyramide

Procedure

Starting with 2-(6-methoxyindan-1-ylidene)ethylamine (hydrochloride) and butyryl chloride, the title compound was synthesized in otherwise the same manner as Example 15 (yield 65%).

Sources & evidence

ORD record: ord-0e608a2a43a64383b2fcc330b53170b5
Source dataset: uspto-grants-1999_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05922771

Reaction notes

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