Propionyl chloride → HCID 54451479, compound

HRID 582218Notes

Reaction equation

HRID 582218 reaction equation
Cl.[F:2][C:3]1[CH:11]=[C:10]2[C:6]([C:7]([CH2:12][CH2:13][NH2:14])=[CH:8][CH2:9]2)=[CH:5][C:4]=1[O:15][CH3:16].[C:17](Cl)(=[O:20])[CH2:18][CH3:19]>>[F:2][C:3]1[CH:11]=[C:10]2[C:6]([C:7]([CH2:12][CH2:13][NH:14][C:17](=[O:20])[CH2:18][CH3:19])=[CH:8][CH2:9]2)=[CH:5][C:4]=1[O:15][CH3:16]

Participants

3

Reactant 2

HCID 62324Propionyl chlorideHCID 70188010HCID 70188010, compound

Product 1

HCID 54451479HCID 54451479, compound

Procedure

Starting with 2-(6-fluoro-5-methoxy-1H-inden-3-yl)ethylamine hydrochloride and propionyl chloride, the title compound was synthesized in otherwise the same manner as Example 8 (yield 83%).

Sources & evidence

ORD record
ord-b3f63e7077a84db4b1b919decaeae0e9
Source dataset
uspto-grants-1999_07
Patent number
US05922771

Reaction notes

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