Butyryl chloride → HCID 54217263, compound
Reaction equation
Cl.[F:2][C:3]1[CH:11]=[C:10]2[C:6]([C:7]([CH2:12][CH2:13][NH2:14])=[CH:8][CH2:9]2)=[CH:5][C:4]=1[O:15][CH3:16].[C:17](Cl)(=[O:21])[CH2:18][CH2:19][CH3:20]>>[F:2][C:3]1[CH:11]=[C:10]2[C:6]([C:7]([CH2:12][CH2:13][NH:14][C:17](=[O:21])[CH2:18][CH2:19][CH3:20])=[CH:8][CH2:9]2)=[CH:5][C:4]=1[O:15][CH3:16]Participants
3
Procedure
Starting with 2-(6-fluoro-5-methoxy-1H-inden-3-yl)ethylamine hydrochloride and butyryl chloride, the title compound was synthesized in otherwise the same manner as Example 8 (yield 80%).
Sources & evidence
- ORD record
- ord-d2fcaa8d164842999f561ef50426608a
- Source dataset
- uspto-grants-1999_07
- Patent number
- US05922771
Reaction notes
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