HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1-propanol → 1-[N-(3-Hydroxypropyl)carbamoyl]-4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1-propanol | HCID 9086 | — |
| Reactant | 4-[1-[3-(Isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid | HCID 10959558 | — |
| Product | 1-[N-(3-Hydroxypropyl)carbamoyl]-4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzene | HCID 54197468 | 76% |
Reaction Steps
By the same procedure as described in the example 1, synthesis was carried out starting with 4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid and using 3-amino-1-propanol. Then, the product was recrystallized using ethyl acetate and ether to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922871 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-25083c4d33e445a7a0de887d10a026e3 |
| Source note | uspto-grants-1999_07 |