HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-1-butanol → 1-[N-(4-Hydroxybutyl)carbamoyl]-4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-1-butanol | HCID 25868 | — |
| Reactant | 4-[1-[3-(Isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid | HCID 10959558 | — |
| Product | 1-[N-(4-Hydroxybutyl)carbamoyl]-4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzene | HCID 86754237 | 84% |
Reaction Steps
By the same procedure as described in the example 1, synthesis was carried out starting with 4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid and using 4-amino-1-butanol. Then, the product was recrystallized using ethyl acetate and isopropyl ether to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922871 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-d2072d2483fe4e36860c608e4afbb49a |
| Source note | uspto-grants-1999_07 |