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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 582319Generated: October 31, 2026

2,2-Diethoxyethylamine → 1-[N-(2,2-Diethoxyethyl)carbamoyl]-4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzene

https://huagongshe.com/reaction/582319

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-DiethoxyethylamineHCID 69524—
Reactant4-[1-[3-(Isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acidHCID 10959558—
Product1-[N-(2,2-Diethoxyethyl)carbamoyl]-4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzeneHCID 5445335576%

Reaction Steps

By the same procedure as described in the example 46, synthesis was carried out starting with 4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid and using 2,2-diethoxyethylamine. Then, the product was recrystallized using ethanol and isopropyl ether to give the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05922871
Source datasetuspto-grants-1999_07
ORD IDord-214b4cc026de449e83d64b336be778da
Source noteuspto-grants-1999_07