N,N-Diethylethylenediamine → HCID 54354633, compound

HRID 582324Notes

Reaction equation

HRID 582324 reaction equation
C[O:2][C:3](=O)[C:4]1[CH:9]=[CH:8][C:7]([C:10]([N:12]2[CH2:17][CH2:16][N:15]([C:18]3[C:23]([NH:24][CH:25]([CH3:27])[CH3:26])=[CH:22][CH:21]=[CH:20][N:19]=3)[CH2:14][CH2:13]2)=[O:11])=[CH:6][CH:5]=1.[CH2:29]([N:31]([CH2:35][CH3:36])[CH2:32][CH2:33][NH2:34])[CH3:30]>>[CH2:29]([N:31]([CH2:35][CH3:36])[CH2:32][CH2:33][NH:34][C:3]([C:4]1[CH:5]=[CH:6][C:7]([C:10]([N:12]2[CH2:13][CH2:14][N:15]([C:18]3[C:23]([NH:24][CH:25]([CH3:27])[CH3:26])=[CH:22][CH:21]=[CH:20][N:19]=3)[CH2:16][CH2:17]2)=[O:11])=[CH:8][CH:9]=1)=[O:2])[CH3:30]

Participants

3

Reactant 2

HCID 60993N,N-DiethylethylenediamineHCID 537116704-[1-[3-(Isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid methyl ester

Product 1

HCID 54354633HCID 54354633, compoundYield 76%

Procedure

By the same procedure as described in the example 45, synthesis was carried out starting with 4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid methyl ester and using N,N-diethylethylenediamine. Then, the product was recrystallized using isopropanol and hexane to give the desired compound.

Workup

  1. customBy the same procedure as described in the example 45, synthesis
  2. customThen, the product was recrystallized

Sources & evidence

ORD record
ord-fb9ba241222146aea591cae5bcf9a386
Source dataset
uspto-grants-1999_07
Patent number
US05922871

Reaction notes

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