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HRID582373

反应详情

EQUATION

反应方程式

HRID 582373 的结构方程式

REACTANTS

反应物

3
结构：O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3
HCID14812

Phosphorus oxide (P4O10)

O10P4

结构：COc1cc(C)cc(OC)c1OC
HCID80922

3,4,5-Trimethoxytoluene

C10H14O3

结构：COc1ccc(Br)c(C)c1C(=O)O
HCID2752992

3-Bromo-6-methoxy-2-methylbenzoic acid

C9H9BrO3

PRODUCTS

生成物

1
结构：COc1cc(C)c(C(=O)c2c(OC)ccc(Br)c2C)c(OC)c1OC
HCID6451057

Metrafenone

C19H21BrO5

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

50B (240 g, 1.0 mol) is reacted with 3,4,5-trimethoxytoluene (182 g; 1.0 mol) in the presence of P2O5 (1.0 kg) and dichloromethane as described in Example 6 yielding white crystals, 220 g (54% ), mp 89-91° C.