HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 582388Generated: October 25, 2026
Nitric Acid → 2,6-Dichloro-5'-nitro-4'-methoxy-2'-methyl-benzophenone
https://huagongshe.com/reaction/582388
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 2,6-Dichloro-4'-methoxy-2'-methyl-benzophenone | HCID 54505258 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,6-Dichloro-5'-nitro-4'-methoxy-2'-methyl-benzophenone | HCID 54492291 | — |
Reaction Steps
2,6-Dichloro-4'-methoxy-2'-methyl-benzophenone (0.75 g; 2.5 mmol) is added to nitric acid (10 ml; 65%). The mixture is stirred at 80° C. for 1 hour. After addition of water the reaction product crystallises and is chromatographically purified (flash column filled with 30 g of silicagel, elution with toluene). White crystalls (0.35 g; 41% y); mp. 156-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05922919 |
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| Source dataset | uspto-grants-1999_07 |
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| ORD ID | ord-951d4c2090904c4db9f028ec34d3f34f |
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| Source note | uspto-grants-1999_07 |
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