Acetic Anhydride → HCID 15871729, compound

Participants

Reaction Steps

(3S,5S)-3-azidomethyl-4-oxa-1-azabicyclo [3,2,0] heptan-7-one (710 mg, 4.23 mmole) was hydrogenated in the presence of acetic anhydride (431 mg, 4.23 mmole) in ethyl acetate (20 ml) at 50 psi for 1 hr. After removal of solvent, the residue was purified by silica gel column chromatography using ethyl acetate-acetone (5:1) as eluent and the title compound was obtained as solid.

Provenance & Evidence