Triphenylphosphine → rac-(1-Isobutyl-2-oxo-pyrrolidin-3-yl)-triphenyl-phosphonium bromide

Participants

Reaction Steps

2.74 g (12.4 mmol) rac-3-Bromo-1-isobutyl-pyrrolidine-2-one were dissolved in 12 ml THF, and 3.43 g (13.1 mmol) triphenylphosphine were added. The mixture was then refluxed for 3 days under argon atmosphere. After cooling to room temperature, the suspension was filtered with suction, the white crystals were washed with ice-cold THF and then dried under high vacuum.

Provenance & Evidence