HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 21833062, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-Acetyl-7-methoxy-4-benzofurancarboxylic acid | HCID 21833041 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21833062 | HCID 21833062 | — |
Reaction Steps
2-Acetyl-7-methoxybenzofuran-4-carboxylic acid (0.12 g) was suspended in anhydrous dichloromethane (4 ml) at room temperature under nitrogen and oxalyl chloride (0.1 ml) added followed by 3 drops of N,N-dimethylformamide. Evaporation in vacuo after 2 h afforded the title compound as a yellow solid (~0.5 g). TLC Rf 0.60 (50% ethyl acetate in hexane)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925636 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-d9c26f8cadea437291fb631ca0b302d6 |
| Source note | uspto-grants-1999_07 |