HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroformate → 2-Cyanoethyl-5-ethoxycarbonylamino-2,3-dihydrobenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 5-Amino-2-cyanoethyl-2,3-dihydrobenzofuran | HCID 54501488 | — |
| Product | 2-Cyanoethyl-5-ethoxycarbonylamino-2,3-dihydrobenzofuran | HCID 53806732 | 87.8% |
Reaction Steps
Starting from 2.6 g (14 mmol) of 5-amino-2-cyanoethyl-2,3-dihydrobenzofuran, 1.45 ml (15.2 mmol) of ethyl chloroformate and 1.7 g (21 mmol) of sodium hydrogencarbonate treated under the conditions described in step 6 of Example 1, 3.2 g of product were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925662 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-033a5d688db6423b8f1d6a17f63b2bdc |
| Source note | uspto-grants-1999_07 |