2-Aminomethyl-1-ethylpyrrolidine → HCID 15870696, compound

HRID 582714Notes

Reaction equation

HRID 582714 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:8]([O:11][CH2:12]/[CH:13]=[C:14](/[CH2:16][CH2:17][CH:18]=[C:19]([CH3:21])[CH3:20])\[CH3:15])=[CH:9][CH:10]=1)[C:5]([OH:7])=O.[NH2:22][CH2:23][CH:24]1[CH2:28][CH2:27][CH2:26][N:25]1[CH2:29][CH3:30]>>[CH2:29]([N:25]1[CH2:26][CH2:27][CH2:28][CH:24]1[CH2:23][NH:22][C:5](=[O:7])[C:4]1[C:8]([O:11][CH2:12]/[CH:13]=[C:14](/[CH2:16][CH2:17][CH:18]=[C:19]([CH3:21])[CH3:20])\[CH3:15])=[CH:9][CH:10]=[C:2]([F:1])[CH:3]=1)[CH3:30]

Participants

3

Reactant 2

HCID 1172952-Aminomethyl-1-ethylpyrrolidineHCID 69853749HCID 69853749, compound

Product 1

HCID 15870696HCID 15870696, compoundYield 84%

Procedure

In a manner identical to Example 15, 3-fluoro-6-geranyloxybenzoic acid (1.46 g) was subjected to a condensation reaction with 2-aminomethyl-1-ethylpyrrolidine (0.7 ml), thereby yielding 1.68 g (84%) of the aimed compound.

Sources & evidence

ORD record
ord-84c4bf9ed3bf4b069df65e9ad5cc7000
Source dataset
uspto-grants-1999_07
Patent number
US05925667

Reaction notes

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