2-Aminomethyl-1-ethylpyrrolidine → HCID 15870697, compound

HRID 582720Notes

Reaction equation

HRID 582720 reaction equation
[CH2:1]([O:6][C:7]1[CH:15]=[CH:14][C:10]([C:11]([OH:13])=O)=[CH:9][N:8]=1)[CH:2]=[C:3]([CH3:5])[CH3:4].[NH2:16][CH2:17][CH:18]1[CH2:22][CH2:21][CH2:20][N:19]1[CH2:23][CH3:24]>>[CH2:23]([N:19]1[CH2:20][CH2:21][CH2:22][CH:18]1[CH2:17][NH:16][C:11](=[O:13])[C:10]1[CH:14]=[CH:15][C:7]([O:6][CH2:1][CH:2]=[C:3]([CH3:4])[CH3:5])=[N:8][CH:9]=1)[CH3:24]

Participants

3

Procedure

In a manner identical to Example 15, 6-prenyloxynicotinic acid (0.70 g) was subjected to a condensation reaction with 2-aminomethyl-1-ethylpyrrolidine (0.90 g, thereby yielding 0.73 g (68%) of the aimed compound.

Sources & evidence

ORD record
ord-aaaec7fcd50349528fb3498aa33eda51
Source dataset
uspto-grants-1999_07
Patent number
US05925667

Reaction notes

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