HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1RS)-cis-3-(Z-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarbonyl chloride → (RS)-3-propyl-3-cyclopentenyl (1RS)-cis-3-(Z-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1RS)-cis-3-(Z-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarbonyl chloride | HCID 11334477 | — |
| Reactant | cis-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropylcarbonyl chloride | HCID 12617358 | — |
| Reactant | (RS)-3-ethyl-4-methyl-3-cyclopenten-1-ol | HCID 15869648 | — |
| Reactant | (RS)-3-propyl-3-cyclopenten-1-ol | HCID 54345607 | — |
| Product | (RS)-3-propyl-3-cyclopentenyl (1RS)-cis-3-(Z-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate | HCID 86754279 | 91% |
Reaction Steps
(RS)-3-propyl-3-cyclopenten-1-ol (500 mg) and (1RS)-cis-2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarbonyl chloride (902 mg) were respectively used instead of (RS)-3-ethyl-4-methyl-3-cyclopenten-1-ol and (1RS)-cis-3-(Z-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarbonyl chloride used in Example 1 above and the reaction procedures were carried out in the same manner as in Example 1 to afford 1150 mg of (RS)-3-propyl-3-cyclopentenyl (1RS)-cis-3-(Z-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate (Compound No. 130). Yield 91% nD24 1.5038
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925676 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-ad53a2d98b3b40ceb255233960d7d78e |
| Source note | uspto-grants-1999_07 |