反应详情

2 g (7 mmol) of ethyl 3-(2-bromoethoxy)-2-methylbenzoate and 1.1 g (7.3 mmol) of potassium thiomethanesulfonate are dissolved in 10 ml absolute ethanol. The reaction mixture is refluxed for 20 hours. The solvent is then distilled off and the residue taken up in methylene chloride and washed with water. The organic phase is dried over sodium sulfate and the solvent is removed. The product of value is purified by column chromatography.

1. temperatureThe reaction mixture is refluxed for 20 hours
2. distillationThe solvent is then distilled off
3. washwashed with water
4. dry with materialThe organic phase is dried over sodium sulfate
5. customthe solvent is removed
6. customThe product of value is purified by column chromatography