HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Benzoic acid, 3-fluoro-4-methyl-, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Fluoro-p-toluic acid | HCID 67687 | — |
| Product | Benzoic acid, 3-fluoro-4-methyl-, ethyl ester | HCID 13489923 | — |
Reaction Steps
150 ml of EtOH are cooled in an ice bath, 10 ml of thionyl chloride are added slowly, 10 g of 3-fluoro-4-methylbenzoic acid are then added and the reaction mixture is stirred, the temperature being allowed to rise to RT. It is refluxed for 2 hours and then concentrated under vacuum to give 10.45 g of the expected product in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925768 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-553be85b467a42fe90a37e77cd627b5e |
| Source note | uspto-grants-1999_07 |