反应详情

The title compound was prepared essentially as in Example 1 by combining 3-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)-1-chloropropane (5.42 g, 11.4 mmol, Example 24) with 5-hexyloxy-2-(4-hydroxyphenyl)pyrimidine (3 g, 10.0 mmol). Product was isolated by addition of water (100 mL) to the resulting mixture, followed by filtration and recrystallization from ethanol. The recrystallized precipitate was dried at about 130° C., and the resulting product was further purified by Kugelrohr distillation (b.p. 170-180° C. at 2.0 torr; yield of 5.4 g).

1. filtrationfollowed by filtration and recrystallization from ethanol
2. customThe recrystallized precipitate was dried at about 130° C.
3. distillationthe resulting product was further purified by Kugelrohr distillation (b.p. 170-180° C. at 2.0 torr; yield of 5.4 g)