HCID 21225291, compound → HCID 21225373, compound

Participants

Reaction Steps

The title compound was prepared essentially as in Example 1 by combining 5-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)pentyl chloride (2.4 g, 5.7 mmol, prepared from 1,5-dichloropentane and 2-(2-(trifluoromethoxy)tetrafluoroethoxy)-2,2-difluoroethanol) with 5-decyl-2-[4-hydroxyphenyl]-1,3,4-thiadiazole (1.4 g, 4.4 mmol, prepared essentially as described by C. Tschierske and D. Girdzivnaite in J. Prakt. Chem. 1991, 135-37). The reaction mixture was quenched by addition of water, and the resulting crude product was recrystallized from ethanol and further purified by Kugelrohr distillation (215-25° C. at 0.01 torr) to provide a yield of 2.3 g.

Provenance & Evidence