N-Iodosuccinimide → HCID 58111422, compound

HRID 58306Notes

Reaction equation

HRID 58306 reaction equation
[Br:1][CH:2]([C:4]1[N:5]=[C:6]2[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[N:7]2[C:8](=[O:10])[CH:9]=1)[CH3:3].[I:16]N1C(=O)CCC1=O>>[Br:1][CH:2]([C:4]1[N:5]=[C:6]2[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[N:7]2[C:8](=[O:10])[C:9]=1[I:16])[CH3:3]

Participants

3

Reactant 2

HCID 120273N-IodosuccinimideHCID 58111411HCID 58111411, compound

Product 1

HCID 58111422HCID 58111422, compoundYield 98%

Procedure

The desired compound was prepared according to the procedure of Example 8, step 3, using 2-(1-bromoethyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one and N-iodosuccinimide as the starting materials in 98% yield. LCMS for C11H11BrIN2O (M+H)+: m/z=392.7, 394.7.

Sources & evidence

ORD record
ord-70e76e3942e2416ba611dc61fee80836
Source dataset
uspto-grants-2016_09
Patent number
US09434746B2

Reaction notes

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