反应详情

温度

60 °C

A mixture comprising 30.4 g of N-benzyloxycarbonyl-3-[3-(4-formylpiperazin-1-yl)-propoxy]-4-methoxybenzylamine, 3.1 g of 5% palladium carbon and 300 ml of ethanol, was stirred at 60° C. for 9 hours under a hydrogen atmosphere. Palladium carbon was filtered off, and then the filtrate was distilled off under reduced pressure to obtain 17.99 g of the above-identified compound as slightly brown oil.

1. filtrationPalladium carbon was filtered off
2. distillationthe filtrate was distilled off under reduced pressure