Ammonium Hydroxide → HCID 21584327, compound

Participants

Reaction Steps

To concentrated sulfuric acid (150 ml) at 0° C. was added 3-ethyl-3,4-dihydro-isoquinoline (20.1 g, 0.12 mols) and potassium nitrate (12.13 g, 0.12 mols). The reaction was allowed to warm to room temperature for 24 h. The reaction was poured onto ice (1.5 l) and then the aqueous phase was made basic with ammonium hydroxide. A solid crystallized and was collected by filtration to yield the title compound (22.3 g, 91%), m.p. 61-62° C.

Provenance & Evidence