HCID 21584307, compound → HCID 21584272, compound

Participants

Reaction Steps

To 2,3-dimethyl-7-nitro-1,2,3,4tetrahydroisoquinoline hydrochloride (2.0 g, 8.24 mmol) in methanol (100 ml) was added a catalytic amount of 10% Pd--C. The mixture was hydrogenated at 50 psi for 1 h, filtered, and concentrated to a solid which was used immediately in the next reaction (1.6 g, 92%), m.p. 215-217° C.

Provenance & Evidence