反应详情

A suspension of 1-methyl-7-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride (2.0 g, 8.75 mmol) in ethanol (100 ml) and a catalytic quantity of 10% Pd--C was hydrogenated until no more hydrogen was taken up. The catalyst was filtered off, the solvent was concentrated to a small volume, ether was added and the precipitated solid was collected and dried: 1.39 g (78%), MS (M+H)+ 163.

1. filtrationThe catalyst was filtered off
2. concentrationthe solvent was concentrated to a small volume, ether
3. additionwas added
4. customthe precipitated solid was collected
5. customdried