1,1,1-Trifluoro-2-iodoethane → HCID 70053807, compound

HRID 583306Notes

Reaction equation

HRID 583306 reaction equation
[CH3:1][O:2][C:3](=[O:30])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([OH:10])[C:5]=1[N:11]([CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[S:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)(=[O:14])=[O:13].I[CH2:32][C:33]([F:36])([F:35])[F:34]>>[CH3:1][O:2][C:3](=[O:30])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:32][C:33]([F:36])([F:35])[F:34])[C:5]=1[N:11]([CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[S:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)(=[O:13])=[O:14]

Participants

3

Reactant 2

HCID 677091,1,1-Trifluoro-2-iodoethaneHCID 70055074HCID 70055074, compound

Product 1

HCID 70053807HCID 70053807, compoundYield 48.4%

Procedure

In the same manner as described in Example 38, 0.40 g (0.937 mmol) of the product of Example 37 and 0.185 mL (1.873 mmol) of 2-iodo-1,1,1-trifluoroethane provided 0.231 g (48%) of the desired product as a colorless oil. Electrospray Mass Spec: 510.3 (M+H)+

Sources & evidence

ORD record
ord-a0d722fbf60c494e9a0c33763e7ed6af
Source dataset
uspto-grants-1999_07
Patent number
US05929097

Reaction notes

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