1-(Chloromethoxy)-2-methoxyethane → HCID 70055473, compound

HRID 583307Notes

Reaction equation

HRID 583307 reaction equation
[CH3:1][O:2][C:3](=[O:30])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([OH:10])[C:5]=1[N:11]([CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[S:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)(=[O:14])=[O:13].[CH2:31](Cl)[O:32][CH2:33][CH2:34][O:35][CH3:36]>>[CH3:1][O:2][C:3](=[O:30])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:31][O:32][CH2:33][CH2:34][O:35][CH3:36])[C:5]=1[N:11]([CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[S:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)(=[O:13])=[O:14]

Participants

3

Reactant 2

HCID 775901-(Chloromethoxy)-2-methoxyethaneHCID 70055074HCID 70055074, compound

Product 1

HCID 70055473HCID 70055473, compoundYield 94%

Procedure

In the same manner as described in Example 38, 0.40 g (0.937 mmol) of the product of Example 37 and 0.134 mL (1.171 mmol) of MEM-Cl provided 0.454 g (94%) of the desired product as a colorless oil. Electrospray Mass Spec: 516.2 (M+H)+

Sources & evidence

ORD record
ord-7101dd78b1c24b4ca00666c2db3bb5d6
Source dataset
uspto-grants-1999_07
Patent number
US05929097

Reaction notes

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