2-Bromobenzyl bromide → HCID 15859217, compound

HRID 583322Notes

Reaction equation

HRID 583322 reaction equation
[CH3:1][O:2][C:3](=[O:24])[C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([CH3:11])[C:5]=1[NH:12][S:13]([C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)(=[O:15])=[O:14].[Br:25][C:26]1[CH:33]=[CH:32][CH:31]=[CH:30][C:27]=1[CH2:28]Br>CCOCC>[CH3:1][O:2][C:3](=[O:24])[C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([CH3:11])[C:5]=1[N:12]([CH2:28][C:27]1[CH:30]=[CH:31][CH:32]=[CH:33][C:26]=1[Br:25])[S:13]([C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)(=[O:15])=[O:14]

Participants

4

Reactant 2

HCID 769652-Bromobenzyl bromideHCID 53963569HCID 53963569, compound

Product 1

HCID 15859217HCID 15859217, compoundYield 73.4%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In the same manner as described in Example 9, 0.699 g (2.0 mmol) of the product of Example 62 and 0.6 g (2.4 mmol) of 2-bromobenzyl bromide provided 0.761 g (73%) of the desired product as a white solid after trituration with ether. Electrospray Mass Spec 518.1(M+H).

Sources & evidence

ORD record
ord-77355b54cd1340efb63348e7e438699b
Source dataset
uspto-grants-1999_07
Patent number
US05929097

Reaction notes

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