HCID 15859217, compound → HCID 21310854, compound

HRID 583327Notes

Reaction equation

HRID 583327 reaction equation
C[O:2][C:3](=[O:32])[C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([CH3:11])[C:5]=1[N:12]([CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[Br:31])[S:13]([C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)(=[O:15])=[O:14]>CCOCC>[Br:31][C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=1[CH2:24][N:12]([S:13]([C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)(=[O:14])=[O:15])[C:5]1[C:6]([CH3:11])=[CH:7][C:8]([CH3:10])=[CH:9][C:4]=1[C:3]([OH:32])=[O:2]

Participants

3

Reactant 1

HCID 15859217HCID 15859217, compound

Product 1

HCID 21310854HCID 21310854, compoundYield 79.3%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In the same manner as described in Example 109, 0.518 g (1.0 mmol) of the product of Example 106 provided 0.4 g (79%) of the desired carboxylic acid as a white solid after trituration with ether. Electrospray Mass Spec 504.0 (M+H).

Sources & evidence

ORD record
ord-babde647674249ef86236e65fe7c1e9a
Source dataset
uspto-grants-1999_07
Patent number
US05929097

Reaction notes

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