HCID 15859218, compound → HCID 21310857, compound

HRID 583329Notes

Reaction equation

HRID 583329 reaction equation
C[O:2][C:3](=[O:32])[C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([CH3:11])[C:5]=1[N:12]([CH2:24][C:25]1[CH:30]=[CH:29][C:28]([Br:31])=[CH:27][CH:26]=1)[S:13]([C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)(=[O:15])=[O:14]>CCOCC>[Br:31][C:28]1[CH:27]=[CH:26][C:25]([CH2:24][N:12]([S:13]([C:16]2[CH:17]=[CH:18][C:19]([O:22][CH3:23])=[CH:20][CH:21]=2)(=[O:15])=[O:14])[C:5]2[C:6]([CH3:11])=[CH:7][C:8]([CH3:10])=[CH:9][C:4]=2[C:3]([OH:32])=[O:2])=[CH:30][CH:29]=1

Participants

3

Reactant 1

HCID 15859218HCID 15859218, compound

Product 1

HCID 21310857HCID 21310857, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In the same manner as described in Example 109, 0.836 g (1.61 mmol) of the product of Example 108 provided 0.584 g (72%) of the desired carboxylic acid as a white solid after trturation with ether. Electrospray Mass Spec 504 (M+H).

Sources & evidence

ORD record
ord-8e52ea81096e4e249d5ab1a170f11d32
Source dataset
uspto-grants-1999_07
Patent number
US05929097

Reaction notes

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