HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → Benzyl-(4-methoxybenzenesulfonylamino)-5-cyano-3-methylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 5-Cyano-2-(4-methoxybenzenesulfonylamino)-3-methyl-benzoic acid | HCID 17866668 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Benzyl-(4-methoxybenzenesulfonylamino)-5-cyano-3-methylbenzoic acid | HCID 17866644 | 51% |
Reaction Steps
In the same manner as described in Example 177, 4.5 g (13 mmol) of the product of Example 180 and 5 mL of benzylbromide provided 3.5 g (51%) of the desired product as brown solid after trituration with ether. m.p. 123° C.; Electrospray Mass Spec 527 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05929097 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-d81bacad74304307b64594758589358b |
| Source note | uspto-grants-1999_07 |