HRID583356

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCCCCCCN(C)C(=O)C=Cc1cc(C)c(N(C)S(=O)(=O)c2ccc(OC)cc2)c(C(=O)OC)c1

HCID70053755

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCN(C)C(=O)C=Cc1cc(C)c(N(C)S(=O)(=O)c2ccc(OC)cc2)c(C(=O)O)c1

HCID70052092

未命名化合物

收率 93%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID21226206

未命名化合物

PROCEDURE

实验过程

In the same manner as described in Example 18, 188 mg (0.35 mmol) of the product of Example 205 provided 170 mg (93%) of the desired carboxylic acid as a white solid after trituration with Hexane/EtOAc (2:1). Electrospray Mass Spec 575(M+HCOOH--H).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-89bbcc4564d54ab395fa5b098c76aa96
来源数据集: uspto-grants-1999_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05929097
来源说明: uspto-grants-1999_07

反应 SMILES

C[O:2][C:3](=[O:38])[C:4]1[CH:9]=[C:8]([CH:10]=[CH:11][C:12](=[O:23])[N:13]([CH3:22])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH:7]=[C:6]([CH3:24])[C:5]=1[N:25]([S:27]([C:30]1[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[CH:32][CH:31]=1)(=[O:29])=[O:28])[CH3:26]>CCCCCC.CCOC(C)=O>[CH3:37][O:36][C:33]1[CH:34]=[CH:35][C:30]([S:27]([N:25]([CH3:26])[C:5]2[C:6]([CH3:24])=[CH:7][C:8]([CH:10]=[CH:11][C:12](=[O:23])[N:13]([CH3:22])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])=[CH:9][C:4]=2[C:3]([OH:38])=[O:2])(=[O:29])=[O:28])=[CH:31][CH:32]=1