N-Ethyl-N-phenylprop-2-enamide → HCID 70124973, compound

HRID 583360Notes

Reaction equation

HRID 583360 reaction equation
[CH3:1][O:2][C:3](=[O:31])[C:4]1[CH:9]=[C:8](Br)[CH:7]=[C:6]([CH3:11])[C:5]=1[N:12]([S:20]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][CH:24]=1)(=[O:22])=[O:21])[CH2:13][C:14]1[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=1.[CH2:32]([N:34]([C:41](=[O:44])[CH:42]=[CH2:43])[C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)[CH3:33]>>[CH3:1][O:2][C:3](=[O:31])[C:4]1[CH:9]=[C:8]([CH:43]=[CH:42][C:41](=[O:44])[N:34]([CH2:32][CH3:33])[C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[CH:7]=[C:6]([CH3:11])[C:5]=1[N:12]([S:20]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][CH:24]=1)(=[O:22])=[O:21])[CH2:13][C:14]1[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 21871650N-Ethyl-N-phenylprop-2-enamideHCID 70053864HCID 70053864, compound

Product 1

HCID 70124973HCID 70124973, compoundYield 65.4%

Procedure

In the same manner as described in Example 203, 550.4 mg (1.0 mmol) of the product of Example 89 and 425 mg (2.43 mniol) of N-ethylacryianilide provided 392 mg (65%) of the desired product as a brown solid. Electrospray Mass Spec 600(M+H).

Sources & evidence

ORD record
ord-0a919efb240c4b6cb5c645e6b18ecf3e
Source dataset
uspto-grants-1999_07
Patent number
US05929097

Reaction notes

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