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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 583380Generated: October 30, 2026

4-Fluorobenzenesulfonyl chloride → 3-Methyl-5-bromo-2-(4-fluoro-benzenesulfonylamino)-benzoic acid

https://huagongshe.com/reaction/583380

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzenesulfonyl chlorideHCID 9588—
ReactantMethyl 2-amino-5-bromo-3-methylbenzoateHCID 2763413—
Product3-Methyl-5-bromo-2-(4-fluoro-benzenesulfonylamino)-benzoic acidHCID 2158449336%

Reaction Steps

By following the procedure of Example 134 the product of Example 133 and 4-flurobenzenesulfonyl chloride provides 5-bromo-2-(4-fluoro-benzenesulfonylamino)-3methyl-benzoic acid as a yellow solid in 36% yield. Electrospray Mass Spec: 386.0 (M-H)-

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05929097
Source datasetuspto-grants-1999_07
ORD IDord-4549ad39d2c94529ac0f5329a4ac072c
Source noteuspto-grants-1999_07