HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tiopronin → 2-[2-[[2-[(4-Sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoylamino]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tiopronin | HCID 5483 | — |
| Reactant | 4-(3-Oxo-1,2-benzothiazol-2-yl)benzenesulfonamide | HCID 462938 | — |
| Product | 2-[2-[[2-[(4-Sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoylamino]acetic acid | HCID 6483559 | 92.3% |
Reaction Steps
This compound was prepared according to the method of Example 132 using 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide and 0.25 g (1.5 mmol) of 2-mercapto-propionylglycine. The product was washed with ether and dried in vacuo to give 0.65 g of the title compound, mp 254-256° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05929114 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-a27834f9303744768d6ea5f76cd6a5e4 |
| Source note | uspto-grants-1999_07 |