Maleic Anhydride → HCID 86753066, compound

Participants

Reaction Steps

A solution with 3.2 g (0.032 mole) of maleic anhydride dissolved in chloroform was added dropwise over 1 hour to 8 g (0.016 mole) of 11,15-dihydroxy-13-octyl-9,13,17-triazapentacosane in a reactor. The resultant mixture was heated to 50° C. and stirred for 6 hours. Thereafter, the solvent was distilled off under reduced pressure, and a solution with 6.0 g (0.048 mole) of sodium sulfite dissolved in 150 ml of water was added to the residue to react them at 60° C. for 7 hours. After completion of the reaction, the reaction mixture was added with 100 ml of additional water and adjusted to pH 7. The thus-adjusted reaction mixture was then desalted by electrodialysis and lyophilized, thereby obtaining 10.6 g (isolation yield: 71%) of sodium 1,15-dicarboxy-6,10-dihydroxy-3,13-dioxo-4,8,12-trioctyl-4,8,12-triaza-1,15-pentadecanedisulfonate.

Provenance & Evidence