HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N-BOC-ethylenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | Di-tert-butyl dicarbonate | HCID 90495 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | N-BOC-ethylenediamine | HCID 187201 | — |
Reaction Steps
Ethylenediamine (16-1) (Aldrich) (18.04 g, 0.50 mol) in CHCl3 (200 ml) was treated with a solution of BOC2O (13.1 g, 0.06 moles) in CHCl3 (100 ml) at room temperature over 1 h. This was stirred for 16 h, filtered, and concentrated to give 16-2 as a clear oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05929120 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-f652c197572143c284b9de7af8207151 |
| Source note | uspto-grants-1999_07 |