HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 10814133, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 86752455 | HCID 86752455 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 10814133 | HCID 10814133 | — |
Reaction Steps
Alkyne 29-6 (60 mg, 0.13 mmol), was suspended in 1.3 mL H2O, 1N NaOH was added until the mixture was homogeneous, 10% Pd/C (12 mg) was added, and an H2 balloon was applied. After 16 h the reaction was filtered, concentrated, and purified by flash chromatography (silica, 12:10:1:1 EtOAc/EtOH/NH4OH/H2O) providing 29-7 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05929120 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-5d764918559d41629e6b584a7b396ea9 |
| Source note | uspto-grants-1999_07 |