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HRID583722

反应详情

EQUATION

反应方程式

HRID 583722 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(Br)Br
HCID11658

Propane, 2,2-dibromo-

C3H6Br2

结构：O=[N+]([O-])c1ccc(N2CCC(n3ccnc3)C2)cc1
HCID12116531

未命名化合物

PRODUCTS

生成物

1
结构：O=[N+]([O-])c1ccc(N2CCC(n3cc[n+](CCCn4cc[n+](C5CCN(c6ccc([N+](=O)[O-])cc6)C5)c4)c3)C2)cc1.[Br-].[Br-]
HCID178526667

未命名化合物

收率 189.3%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCO.CN(C)C=O
溶剂HCID86593149

未命名化合物

CONDITIONS

反应条件

温度
115 °C

PROCEDURE

实验过程

3.5 g (0.0135 mol) of 1-[1-(4-nitrophenyl)pyrrolidin-3-yl]-1H-imidazole were heated to 100° C. in 12 ml of a pentanol/DMF mixture (50/50). 1 g (0.005 mol) of dibromopropane was added. The reaction medium was heated at 115° C. for 17 hours. The precipitate was filtered off while hot and washed with pentanol and then with ether. After draining by suction and drying the precipitate, 3.4 g of yellow powder (4) were obtained. 33% yield.

WORKUP

后处理

  1. filtrationThe precipitate was filtered off while hot and
  2. washwashed with pentanol
  3. customdrying the precipitate