HCID 178526667, compound → 3-[1-(4-aminophenyl)pyrrolidin-3-yl]-1-(3-{1-[1-(4-aminophenyl)pyrrolidin-3-yl]-1H-imidazol-3-ium-3-yl}propyl)-1H-imidazol-3-ium dibromide

Participants

Reaction Steps

3.2 g (0.0044 mol) of derivative (4) above dissolved in a mixture of 60 ml of water/300 ml of ethanol were hydrogenated in the presence of palladium-on-charcoal under a hydrogen pressure of 9 bar and at 75° C. After filtering off the catalyst, the expected derivative (5) was isolated in the form of the hydrobromide. 3.4 g of white powder were obtained; 94% yield.

Provenance & Evidence