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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 583741Generated: October 30, 2026

1-methyl-1-nitroso-3-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea → Citicoline sodium

https://huagongshe.com/reaction/583741

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-methyl-1-nitroso-3-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]ureaHCID 2733335—
ReactantHCID 16211925HCID 16211925—
SolventWaterHCID 962—
ProductCiticoline sodiumHCID 36605—

Reaction Steps

CDP-choline Na was dissolved in distilled water and orally administered at a dose of 100 mg/kg once a day starting from the time point when 5 weeks passed from the administration of streptozotocin.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06924272B2
Source datasetuspto-grants-2005_08
ORD IDord-d89d1ae14a3640de84a6edbb177f06a2
Source noteuspto-grants-2005_08