Piperonyl alcohol → HCID 69693236, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described for Example 2 using carbonyldiimidazole (1.1 g, 6.8 mmol), 2,4-thiophene-dicarboxylic acid (0.5 g, 2.9 mmol) and piperonyl alcohol (0.45 g, 2.9 mmol). Acidification of the aqueous workup mixture with dilute hydrochloric acid prior to filtration afforded 0.71 g of thiophene-2,4-dicarboxylic acid di-1,3-benzodioxol-5-ylmethyl ester. Recrystallization of a sample from methanol followed by trituration in ethyl acetate then ether and drying gave product with a mp 164-165° C.

Provenance & Evidence