1,2,3-Trifluoro-5-nitrobenzene → 4-[(2,6-Difluoro-4-nitrophenyl)sulfanyl]pyridine

HRID 583821Notes

Reaction equation

HRID 583821 reaction equation
[SH:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[F:8][C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[C:11]([F:18])[C:10]=1F>>[F:8][C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[C:11]([F:18])[C:10]=1[S:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 27827931,2,3-Trifluoro-5-nitrobenzeneHCID 178418431pyridine-4-thiol

Product 1

HCID 223436194-[(2,6-Difluoro-4-nitrophenyl)sulfanyl]pyridine

Procedure

is synthesized analogously to C2 from 4-mercaptopyridine and 1,2,3-trifluoro-5-nitrobenzene.

Sources & evidence

ORD record
ord-9ff23bdd419c40bbbd44675f6b332746
Source dataset
uspto-grants-2005_08
Patent number
US06924290B2

Reaction notes

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