反应详情

A solution of chlorosulfonic acid at 0° C. (5 mL, 75 mmol) was treated portionwise with 1-methylindoline (CAS No. [824-21-5], 1.96 g, 14.7 mmol), warmed to room temperature, heated at 75° C. for 40 minutes, cooled, and poured onto ice to provide a solid. The solid was collected by suction filtration, washed with water, and dried to provide 927 mg of the desired product.

1. temperatureheated at 75° C. for 40 minutes
2. temperaturecooled
3. additionpoured onto ice
4. customto provide a solid
5. filtrationThe solid was collected by suction filtration
6. washwashed with water
7. customdried