HCID 22344717, compound → HCID 11508581, compound

Participants

Reaction Steps

A room temperature solution of Example 90A (75 mg, 0.20 mmol) in ethanol (5 mL) was treated with 10% Pd/C (10 mg), stirred under a hydrogen atmosphere for 3 hours, heated to reflux, stirred for 3 hours, cooled to room temperature, filtered through diatomaceous earth (Celite®), and concentrated. The concentrate was purified by flash column chromatography with 50% ethyl acetate/dichloromethane to provide the desired product.

Provenance & Evidence