Trifluoroacetic acid → HCID 22344765, compound

Participants

Reaction Steps

1.4 g of tert-butyl (5-tert-butoxycarbonylmethyl-2,6-dioxoperhydro-1,5-diazocin-1-yl)acetate (starting material A3) are dissolved in 6 ml of dichloromethane, and 6 ml of trifluoroacetic acid are added. The mixture is stirred overnight and then concentrated using a rotary evaporator, and the residue is triturated with ethyl acetate/petroleum ether (1:1). The residue is filtered off with suction and dried under reduced pressure. This gives 0.89 g of the title compound which starts to melt at 250° C. (decomposition); the mass spectrum shows the molecular peaks MH+ and MNH4+ at 259 and 276 Da, respectively.

Provenance & Evidence